Taking the full advantage of the ChewMed® platform
The nicotine gum is just the first application of our compressed gum. The ChewMed® platform is unusually well suited for administration of other generic APIs as well as non-medical substances. Over time our aim is to develop different applications within various therapy areas, such as allergy, cough & cold, pain management, erectile dysfunction and others.
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Drug administration through the oral cavity has been a reality for a long time. It has several advantages over traditional tablet administration. Among other things, you avoid the first-pass metabolism and the uptake to the systemic circulation is effective and immediate. It gives a fast onset of effect and fewer side effects than if the drug was administered via the gastrointestinal tract. In addition, with medicated gums there is no need for adding water at intake. Not least important, chewing gum offers the user a refreshing taste experience making treatment more pleasant. That is why we believe that medicated gums, or so called active gums or functional gums, are the future way of drug administration.
As a first step, Enorama Pharma has chosen to investigate the possibilities to develop a medicated gum for treatment of allergic rhinitis, a market with huge potential. An initial technical evaluation has been performed regarding some active substances. The analysis points out seven APIs as potential candidates. Enorama Pharma is currently searching for partners within allergic rhinits.
Enorama Pharma entered into an agreement with the company MediiGum LLC to conduct a screening study of active substances in the Cough & Cold therapy area. The preliminary study investigated the suitability of active substances for chewing gum administration. MediiGum LLC (Florida, USA) is a newly formed company with plans to launch a number of medical chewing gum formulations in the future. The cost of this initial analysis was covered by MediiGum LLC.
The screening study was completed in June 2019 and an evaluation of the study results has been initiated with the client.